Yep. All the game needs is an assortment of cards (in a similar way to CAH or Funemployed), so you can play with any set - especially now they’re consolidating the small boxes into larger ones.
My only real criticism of the game is quite a few cards are very very American (lots of people I’ve never heard of as a Brit!!) and very very topical - to the point where they’d be recognisable for only a few months. But looks like they’re addressing that with the culling of cards in this edition. Even this doesn’t affect the game too badly since the same cards come out multiple times in a game so recognising the obscure cards coming back round again is half the fun.